ALEXANDRIA, Va., June 18 -- United States Patent no. RE50,453, issued on June 10, was assigned to Vertex Pharmaceuticals Inc. (Boston).
"Indole derivatives as CFTR modulators" was invented by Sara S. Hadida Ruah (La Jolla, Calif.), Peter D. J. Grootenhuis (San Diego), Fredrick Van Goor (San Diego), Jinglan Zhou (San Diego), Brian Bear (Oceanside, Calif.), Mark T. Miller (San Diego), Jason McCartney (Cardiff by the Sea, Calif.), Mehdi Michel Djamel Numa (San Diego) and Xiaoqing Yang (San Diego).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments ...