ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,227,765, issued on Feb. 18, was assigned to Vertex Pharmaceuticals Inc. (Boston).
"Differentiation of pancreatic endocrine cells" was invented by George Harb (Boston) and Chunhi Xie (Belmont, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are compositions and methods related to differentiation of stem cells into pancreatic endocrine cells. In some aspects, the methods provided herein relate to generation of pancreatic Beta cell, Alpha cell, Delta cells, and EC cells in vitro. In some aspects, the disclosure provides pharmaceutical compositions including the cells generated according to the methods disclosed herein, as well as meth...