US Patent Issued to Versantis on Sept. 30 for "Method for preparing transmembrane pH-gradient vesicles" (Swiss, Canadian Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,427,112, issued on Sept. 30, was assigned to Versantis AG (Zurich).

"Method for preparing transmembrane pH-gradient vesicles" was invented by Jean-Christophe Leroux (Zurich), Vincent Forster (Zurich) and Valentina Agostoni (Montreal).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for preparing transmembrane pH-gradient vesicles is provided. This method includes the following steps: a) preparing vesicles made from at least one matrix substance in an aqueous medium having an osmolarity of not more than 200 mOsm/l, wherein the matrix substance is chosen from the group consisting of amphiphilic lipids and amphiphilic block copolymers, b) transferri...