US Patent Issued to Verily Life Sciences on April 8 for "Detecting false positive variant calls in next-generation sequencing" (California Inventors)

ALEXANDRIA, Va., April 9 -- United States Patent no. 12,272,431, issued on April 8, was assigned to Verily Life Sciences LLC (Dallas).

"Detecting false positive variant calls in next-generation sequencing" was invented by Mark Andrew DePristo (Palo Alto, Calif.) and Ryan Poplin (Palo Alto, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for detecting false positive variant calls in a next generation sequencing analysis pipeline involves obtaining a plurality of read pileup windows associated with a first sample genome. The method also involves obtaining, for each reference nucleotide position represented in the plurality of read pileup windows, a label indicating that the reference nucleotide ...