ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,913, issued on Feb. 10, was assigned to VedaBio Inc. (San Diego).

"Signal boost cascade assay" was invented by Anurup Ganguli (San Diego), Ashish Pandey (San Diego), Ariana Mostafa (San Diego) and Jacob Berger (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to compositions of matter and assay methods used to detect one or more target nucleic acids of interest in a sample. The compositions and methods provide signal boost upon detection of target nucleic acids of interest in less than one minute and in some instances instantaneously at ambient temperatures down to 16deg C. or less, without amplification of the...