US Patent Issued to Vaxcyte on March 18 for "Carrier-protein polysaccharide conjugation methods" (California Inventors)

ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,454, issued on March 18, was assigned to Vaxcyte Inc. (San Carlos, Calif.).

"Carrier-protein polysaccharide conjugation methods" was invented by Jeffery C. Fairman (Mountain View, Calif.), Neeraj Kapoor (Foster City, Calif.), Lucy Estella Pill (Burlingame, Calif.) and Scott Snyder (Union City, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods of preparing heteroaryl-containing compounds, wherein an azide-alkyne cycloaddition is accelerated in the presence of lauryldimethylamine oxide (LDAO). The present disclosure further provides conjugates of polypeptides and antigens prepared using such methods."

The ...