ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,502,379, issued on Dec. 23, was assigned to Vanda Pharmaceuticals Inc. (Washington).

"Ponesimod for avoiding worsening of fatigue-related symptoms in multiple sclerosis patients" was invented by Michel Burcklen (Allschwil, Switzerland), Tarek El Akkad (Chester, N.J.), Brian Hennessy (Allschwil, Switzerland), Andrea Vaclavkova (Allschwil, Switzerland) and Alexander Keenan (Raritan, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to methods of treating multiple sclerosis using Ponesimod. In certain aspects, these include methods of avoiding worsening of fatigue-related symptoms in a human patient who has had no prior disease mod...