US Patent Issued to University of Washington on Nov. 18 for "Methods and compositions for reprogramming Muller Glia" (Washington Inventors)

ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,472,270, issued on Nov. 18, was assigned to University of Washington (Seattle).

"Methods and compositions for reprogramming Muller Glia" was invented by Thomas A. Reh (Seattle), Nikolas L. Jorstad (Seattle) and Levi Todd (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "Nucleic acid molecules and compositions, and methods using the same are provided herein for intraocular gene-based delivery and expression of two or more proneural bHLH transcription factors in the retina. The nucleic acid molecules, compositions and methods disclosed herein stimulate regeneration of retinal interneurons from retinal Muller glia (MG) and reprogram the MG into bipol...