ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,661, issued on Dec. 30, was assigned to University of Washington and SEATTLE CHILDREN'S HOSPITAL.
"Compositions and methods related to aptamer-based reversible cell selection" was invented by Suzie H. Pun (Seattle), Michael Jensen (Seattle), Nataly Kacherovsky (Seattle) and Ian Cardle (Seattle).
According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein is a reversible aptamer selection technology for production-scale isolation of label-free cells (e.g., CD8+ T cells). Provided herein are methods for isolating a cell of interest from a biological sample by contacting the biological sample with an aptamer that specifically binds a cell surface mar...