ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,453,716, issued on Oct. 28, was assigned to University of Vermont and State Agricultural College (Burlington, Vt.).

"Small molecule antagonist to PACAP receptor and uses thereof" was invented by Victor May (Essex, Vt.), Matthias Brewer (Williston, Vt.) and Jianing Li (South Burlington, Vt.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to compounds that demonstrate efficacy in blocking PACAP receptors (e.g. PAC1) and associated methods of treating neurological diseases or disorders using the disclosed compounds. The neurological diseases or disorders include, but are not limited to, stress-related diseases (e.g. chronic stress, pos...