US Patent Issued to University of South Florida on Nov. 11 for "Methods of reducing cognitive impairment and learning and memory deficits caused by a P301L mutation in microtubule-associated protein tau (mapt) protein in patients with alzheimer's disease using an AAV9 vector encoding a phosphomimetic (S/D) Hsp22 mutant" (Florida Inventors)

ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,465,656, issued on Nov. 11, was assigned to University of South Florida (Tampa, Fla.).

"Methods of reducing cognitive impairment and learning and memory deficits caused by a P301L mutation in microtubule-associated protein tau (mapt) protein in patients with alzheimer's disease using an AAV9 vector encoding a phosphomimetic (S/D) Hsp22 mutant" was invented by Laura Jenelle Blair (Tampa, Fla.) and Paula C. Bickford (Tampa, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of improving cognition, learning and memory in a patient having a tauopathy neurodegenerative disease by the administration of small heat shock protein 22 (Hsp22) is presente...