ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,535,487, issued on Jan. 27, was assigned to UNIVERSITY OF SOUTH CAROLINA (Columbia, S.C.).

"Detection of fumarate-derived modification in a test sample" was invented by Norma Frizzell Catledge (West Columbia, S.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Examination of a test sample to determine the presence or quantity of succination of proteins is described. Examination can be via protein hydrolysis in total succination determination or via enzymatic digestion of isolated proteins and determination of the presence or quantity of modified peptides. The methods can be utilized for determination of excessive succination of lymph system proteins, wh...