ALEXANDRIA, Va., June 9 -- United States Patent no. 12,286,442, issued on April 29, was assigned to UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh).

"Methods and materials for increasing transcription factor eb polypeptide levels" was invented by Beibei Chen (Sewickley, Pa.), Toren Finkel (Pittsburgh) and Yuan Liu (Sewickley, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This document provides methods and materials for increasing TFEB polypeptide levels. For example, compounds (e.g., organic compounds) having the ability to increase TFEB polypeptide levels within cells and/or within a nucleus of cells, formulations containing compounds having the ability to increase ...