ALEXANDRIA, Va., July 16 -- United States Patent no. 12,358,989, issued on July 15, was assigned to UNIVERSITY OF OSLO (Oslo, Norway) and Nykode Therapeutics ASA (Oslo, Norway).
"HLA binding vaccine moieties and uses thereof" was invented by Gunnveig Grodeland (Oslo, Norway), Bjarne Bogen (Oslo, Norway) and Agnete B. Fredriksen (Oslo, Norway).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to an immunoglobulin derived single-chain fragment variable (scFv) that broadly binds HLA II molecules and uses thereof. In particular, targeting of an antigen to antigen presenting cells with the HLAII-specific targeting unit provided herein find use in enhancing immune responses after vaccinat...