US Patent Issued to University of Massachusetts on Oct. 28 for "Minigene therapy" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,702, issued on Oct. 28, was assigned to University of Massachusetts (Westborough, Mass.).

"Minigene therapy" was invented by Guangping Gao (Worcester, Mass.) and Hemant Khanna (Worcester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure relate to compositions and methods useful for treating ocular ciliopathies, for example Leber congenital amaurosis (LCA). In some embodiments, the disclosure provides isolated nucleic acids comprising a transgene encoding a CEP290 protein fragment, and methods of treating ocular ciliopathies using the same."

The patent was filed on June 30, 2023, under Application No. 18/345,366.

*For ...