US Patent Issued to University of Massachusetts on May 27 for "SOD1 dual expression vectors and uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,587, issued on May 27, was assigned to University of Massachusetts (Westborough, Mass.).

"SOD1 dual expression vectors and uses thereof" was invented by Christian Mueller (Worcester, Mass.) and Robert H. Brown Jr. (Worcester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "In some aspects, the disclosure relates to compositions and methods useful for inhibiting SOD1 expression in cells (e.g., cells of a subject). In some embodiments, the disclosure describes isolated nucleic acids engineered to express an inhibitory nucleic acid targeting endogenous SOD1 and an mRNA encoding a hardened SOD1 protein. In some embodiments, compositions and methods...