US Patent Issued to University of Massachusetts on June 10 for "Enzymatic methods to generate high yields of sequence specific RNA oligonucleotides with extreme precision" (Massachusetts Inventors)

ALEXANDRIA, Va., June 18 -- United States Patent no. 12,325,873, issued on June 10, was assigned to University of Massachusetts (Boston).

"Enzymatic methods to generate high yields of sequence specific RNA oligonucleotides with extreme precision" was invented by Craig Martin (Amherst, Mass.), Elvan Cavac (Northampton, Mass.), Kithmie Harshana Malagodapathiranage (Amherst, Mass.), Shuo Sui (Sunderland, Mass.), Sarah L. Perry (Belchertown, Mass.) and Yasaman Gholamalipour (Worcester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are synthetic methods for producing sequence-specific RNA oligonucleotides that eliminate impurities produced in prior art methods. In one aspect, an end-protec...