US Patent Issued to UNIVERSITY OF MASSACHUSETTS on July 1 for "Dual-acting siRNA based modulation of C9orf72" (Massachusetts Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,839, issued on July 1, was assigned to UNIVERSITY OF MASSACHUSETTS (Westborough, Mass.).

"Dual-acting siRNA based modulation of C9orf72" was invented by Anastasia Khvorova (Westborough, Mass.), Bruno Miguel da Cruz Godinho (Worcester, Mass.) and James W. Gilbert (Worcester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure relates to novel C9ORF72 targeting sequences. Novel sense and antisense dual-targeting oligonucleotides for the treatment of neurodegenerative diseases are also provided."

The patent was filed on March 26, 2021, under Application No. 17/213,887.

*For further information, including images, charts and tables, ple...