US Patent Issued to University of Massachusetts on Jan. 13 for "Aav vectors encoding NF1 and uses thereof" (Massachusetts Inventor)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,845, issued on Jan. 13, was assigned to University of Massachusetts (Westborough, Mass.).

"Aav vectors encoding NF1 and uses thereof" was invented by Miguel Sena Esteves (Westford, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure relate to compositions and methods of treating certain genetic disease (e.g., Neurofibromatosis type I) by delivering functional neurofibromin 1(NF1) protein (e.g., mini-NF1 protein and/or full-length NF1 protein) to target cell (e.g., cells and/or tissue of a subject). The disclosure is based, in part, on isolated nucleic acids (e.g., rAAV vectors) and rAAVs engineered to express a functional ...