US Patent Issued to University of Massachusetts on Dec. 9 for "Methods and compositions for treating metabolic imbalance in neurodegenerative disease" (Massachusetts Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,491,235, issued on Dec. 9, was assigned to University of Massachusetts (Westborough, Mass.).

"Methods and compositions for treating metabolic imbalance in neurodegenerative disease" was invented by Guangping Gao (Worcester, Mass.) and Dominic Gessler (Worcester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "In some aspects, the disclosure relates to compositions and methods useful for the diagnosis and treatment of neurodegenerative diseases, such as leukodystrophies (e.g., Canavan Disease). In some embodiments, the methods comprise administering to a subject an N-acetylaspartate (NAA)-depleting agent or an N-acetylaspartate (NAA)-depleting agent ...