ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,554, issued on Aug. 5, was assigned to UNIVERSITY OF MASSACHUSETTS (Westborough, Mass.).
"Anti-C9ORF72 oligonucleotides and related methods" was invented by Robert H. Brown Jr. (Needham, Mass.), Jonathan K. Watts (Worcester, Mass.), Helene Tran (Shrewsbury, Mass.) and Michael Moazami (Worcester, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides antisense compounds, methods, and compositions for silencing C9ORF72 transcripts. The present disclosure provides antisense compounds, methods, and compositions for the treatment, prevention, or amelioration of diseases, disorders, and conditions associated with C9ORF72 in a ...