US Patent Issued to University of Hawaii on July 29 for "Compositions and methods for the synthesis and identification of covalent aptamers" (Hawaii Inventor)

ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,694, issued on July 29, was assigned to University of Hawaii (Honolulu).

"Compositions and methods for the synthesis and identification of covalent aptamers" was invented by Iain Seido MacPherson (Honolulu).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for preparing and identifying aptamers and aptamer-protein conjugates are provided. The use of a nucleotide analog functionalized with an amine-reactive cross-linker facilitates covalent cross-linking of the aptamer to a protein, in particular site-specific cross-linking to the Fc domain of an antibody."

The patent was filed on Nov. 13, 2019, under Application No. 17/289,767....