US Patent Issued to University of Florida Research Foundation on Oct. 7 for "Aptamer assemblies for protein crosslinking" (Florida Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,433,937, issued on Oct. 7, was assigned to University of Florida Research Foundation Inc. (Gainesville, Fla.).

"Aptamer assemblies for protein crosslinking" was invented by Bryan D. James (Gainesville, Fla.) and Josephine Allen (Gainesville, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein is the use of DNA aptamer assemblies of varying DNA length, structure, and sequence to both bind to collagen and other proteins, to then act as a biocompatible, degradable, reversible, or permanent 3D crosslinkers between proteins, and to service as a biologically functional material when using the appropriate aptamer sequence. Therefore, disclosed ...