ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,444, issued on May 13, was assigned to University of Florida Research Foundation Inc. (Gainesville, Fla.).
"AAV-based gene therapies for treatment of autoimmune diseases" was invented by Brad E. Hoffman (Gainesville, Fla.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are AAV viral-based vector compositions useful in delivering a variety of nucleic acid segments, including those encoding therapeutic polypeptides to selected mammalian host cells for use in therapeutic autoimmune modalities, including, for example, the in vivo induction of immunological tolerance via a liver-directed AAV-based gene therapeutic regimen for treating and/or ame...