ALEXANDRIA, Va., July 23 -- United States Patent no. 12,364,707, issued on July 22, was assigned to University of Florida Research Foundation Inc. (Gainesville, Fla.).
"Manipulation of eIF3 to modulate repeat associated non-ATG (RAN) translation" was invented by Laura Ranum (Gainesville, Fla.), Fatma Ayhan (Lewisville, Texas) and Tao Zu (Gainesville, Fla.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and compositions for modulating repeat non-ATG protein (RAN protein) translation are provided. In some aspects, the disclosure relates to methods for treating a subject having a disease associated with RAN protein translation by administering the subject a modulator of eIF3 or an eIF3 subunit, or an ant...