ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,527, issued on March 18, was assigned to UNIVERSITY OF FLORIDA RESEARCH FOUNDATION Inc. (Gainesville, Fla.) and EMMUNE INC. (Juno Beach, Fla.).

"CD4 muteins and methods of using the same" was invented by Michael Farzan (Juno Beach, Fla.), Matthew Gardner (Jupiter, Fla.), Ina Fetzer (Palm Beach Gardens, Fla.), Michael Alpert (Jupiter, Fla.) and Charles Bailey (Jupiter, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to proteins that contain the CD4 domain 1 and the CD4 domain 2 (CD4 D1D2), wherein the CD4 D1D2 contains one or more mutations compared to wild-type human CD4 D1D2, and to methods of using the proteins for treat...