ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,559, issued on Aug. 5, was assigned to UNIVERSITY OF ESSEX ENTERPRISES Ltd. (Essex, Great Britain).
"Enzymatic nucleic acid molecules" was invented by Greg Brooke (Essex, Great Britain), Antonio Marco Castillo (Essex, Great Britain) and Angela Pine (Essex, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "Certain aspects of the present invention relate to methods and reagents for the treatment of prostate cancer. Also included in the present invention is an enzymatic nucleic acid molecule ("DNAzyme") comprising a catalytic core and two specific binding arms complementary to a nucleic acid sequence comprised in an Androgen Receptor mRNA mol...