ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,587, issued on July 1, was assigned to UNIVERSITY OF DURHAM (Great Britain).

"Synthetic retinoids for use in RAR activation" was invented by Andrew Whiting (Durham, Great Britain), David Chisholm (Durham, Great Britain), Iain Greig (Aberdeenshire, Great Britain), Thabat Khatib (Aberdeenshire, Great Britain) and Peter McCaffery (Aberdeenshire, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds of formula I: in which A1-A7 and R1 to R5 are defined herein, for use in the treatment of a condition or disease which is alleviated by the activation of retinoic acid receptors (RAR). The invention also relat...