US Patent Issued to University of Dundee on July 8 for "Activity based probes" (British Inventors)

ALEXANDRIA, Va., July 9 -- United States Patent no. 12,351,857, issued on July 8, was assigned to University of Dundee (Dundee, Great Britain).

"Activity based probes" was invented by Satpal Virdee (Dundee, Great Britain), Sunil Mathur (Dundee, Great Britain) and Adam Fletcher (Dundee, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to the development of novel photocrosslinking activity based probes (ABPs) and their uses. Specifically, ubiquitin-charged E2 conjugating enzymes are engineered and shown to be effective ABPs of RING ubiquitin E1 and E3 ligases as well as deubiquitination enzymes."

The patent was filed on Aug. 28, 2020, under Application No. 17/753,...