ALEXANDRIA, Va., March 19 -- United States Patent no. 12,251,378, issued on March 18, was assigned to University of Connecticut (Farmington, Conn.).

"Long-acting local anesthetic formulation" was invented by Rajesh V. Lalla (West Hartford, Conn.), Diane J. Burgess (Storrs, Conn.) and Tingting Li (Mansfield Center, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions that include a bupivacaine salt are provided. The compositions may include bupivacaine linoleate, bupivacaine linolenate or bupivacaine laurate, at least one thermosensitive polymer, and at least one mucoadhesive or dermoadhesive agent. Also provided are methods for the treatment of an inflammatory or ulcerative condition with the di...