US Patent Issued to University Health Network on March 4 for "Peptide-HLA complexes and methods of producing same" (Canadian, Japanese, Australian Inventors)

ALEXANDRIA, Va., March 5 -- United States Patent no. 12,240,886, issued on March 4, was assigned to University Health Network (Toronto).

"Peptide-HLA complexes and methods of producing same" was invented by Naoto Hirano (Toronto), Munehide Nakatsugawa (Sapporo, Japan), Muhammed Aashiq Rahman (Brisbane, Australia) and Kenji Murata (Toronto).

According to the abstract* released by the U.S. Patent & Trademark Office: "There is provided herein, the use of mammalian derived HLA class I molecule for in vitro peptide exchange. For example, there is provided a method of producing an HLA class I molecule complexed to a pre-selected peptide comprising: (a) providing a mammalian derived HLA class I molecule complexed to an existing peptide; (b) incu...