ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,554, issued on Sept. 23, was assigned to University College Cardiff Consultants Ltd. (Cardiff, Great Britain).
"Method for the isolation of double-strand breaks" was invented by Simon Reed (Cowbridge, Great Britain), Felix Dobbs (Cambridge, Great Britain) and Patrick Van Eijk (Cardiff, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a method for determining the number and nature of DNA double-strand breaks (DSBs) in a nucleic acid sample, ideally gDNA; a kit of parts for performing the method including at least a plurality of oligonucleotides for ligating to the nucleic acid sample and providing at least a firs...