US Patent Issued to UNIVERSITY COLLEGE CARDIFF CONSULTANTS on June 3 for "Modified adenoviruses" (British, Finnish Inventors)

ALEXANDRIA, Va., June 4 -- United States Patent no. 12,318,418, issued on June 3, was assigned to UNIVERSITY COLLEGE CARDIFF CONSULTANTS Ltd. (Wales, Great Britain).

"Modified adenoviruses" was invented by Alan Parker (South Glamorgan, Great Britain) and Hanni Uusi-Kerttula (Helsinki).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention concerns a modified oncolytic adenovirus of serotype Ad5; a pharmaceutical composition comprising same; and a method of treating cancer using same wherein said modified adenovirus comprises at least one point mutation(s) in the hexon hypervariable region 7 (HVR7 mutation) to prevent virus binding with coagulation factor 10 (FX); at least one point mutation(s) in the fi...