ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,504,408, issued on Dec. 23, was assigned to UNIVERSITEIT LEIDEN (Leiden, Netherlands).

"Apparatus comprising a guard column" was invented by Amy C. Harms (Leiden, Netherlands), Thomas Hankemeier (Leiden, Netherlands) and Tom Van Der Laan (Leiden, Netherlands).

According to the abstract* released by the U.S. Patent & Trademark Office: "A chromatography analysis apparatus (30) comprises: a fractionation device (32) for receiving a sample, the fractionation device (32) defining a sample flow path that includes a guard column; and a fractionation output analyser (34), wherein a fractionation output of the guard column is provided to an input of the fractionation output analyser (34) for ...