ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,383,602, issued on Aug. 12, was assigned to UNIVERSITAT ZURICH (Zurich) and UNIVERSITAT BASEL (Basel, Switzerland).
"HLA-B57 open conformers" was invented by Osiris Marroquin Belaunzaran (Zurich), Ulf Petrausch (Zurich) and Christoph Renner (Zurich).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a HLA-B57 open conformer or a HLA-B57 Fc fusion protein for use in the treatment or prevention of cancer. The Fc open conformer comprises or consists of a first and a second monomer, and each monomer comprises a HLA-B57 chain. The Fc fusion protein further comprises a protein stabilizing polypeptide sequence and optionally an amino acid l...