ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,323, issued on Aug. 5, was assigned to UNIVERSITAT STUTTGART (Stuttgart, Germany).

"IgM and IgE heavy chain domain 2 as covalently linked homodimerization modules for the generation of fusion proteins with dual specificity" was invented by Roland Kontermann (Nurtingen, Germany), Oliver Seifert (Stuttgart, Germany) and Aline Plappert (Stuttgart, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a polypeptides comprising a heavy chain domain 2 (HD2) from IgM or IgE and at least one pharmaceutically active moiety, complexes thereof and their use for therapy and prophylaxis."

The patent was filed on Nov. 9, 2020, unde...