ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,458, issued on Oct. 21, was assigned to UNIVERSITAT BERN (Bern, Switzerland).
"Ligands to light or its receptor LTBR for use in haematologic malignancies" was invented by Adrian Ochsenbein (Hinterkappelen, Switzerland), Sabine Hopner (Bern, Switzerland) and Carsten Riether (Bern, Switzerland).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a non-agonist ligand, particularly an antibody, that specifically binds to LIGHT or its receptor LTBetaR thereby interrupting the interaction of LIGHT with LTBetaR for use in treatment of a haematologic malignancy."
The patent was filed on June 14, 2019, under Application No. 17/252...