ALEXANDRIA, Va., July 23 -- United States Patent no. 12,365,922, issued on July 22, was assigned to UNIVERSITAT BASEL (Basel, Switzerland).
"Allele editing and applications thereof" was invented by Mara Kornete (Basel, Switzerland) and Lukas Jeker (Riehen, Switzerland).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a method to determine a homology directed repair (HDR) event within a eukaryotic cell, wherein the cell expresses a first isoform of a surface protein, which is different from a second isoform of said surface protein with regard to an amino acid marker. The method comprises the steps of inducing a DNA double strand break, providing a HDR template DNA construct comprising th...