US Patent Issued to UNIVERSITA' DEL PIEMONTE ORIENTALE on Nov. 4 for "Vector with an endothelial-specific promoter for treating factor V, VII, VIII, or IX deficiency" (Italian Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,225, issued on Nov. 4, was assigned to UNIVERSITA' DEL PIEMONTE ORIENTALE (Vercelli, Italy).

"Vector with an endothelial-specific promoter for treating factor V, VII, VIII, or IX deficiency" was invented by Antonia Follenzi (Vercelli, Italy), Simone Merlin (Vercelli, Italy), Ester Borroni (Vercelli, Italy), Chiara Borsotti (Vercelli, Italy), Valentina Bruscaggin (Vercelli, Italy) and Silvia Zucchelli (Vercelli, Italy).

According to the abstract* released by the U.S. Patent & Trademark Office: "Sequences derived from Stabilin-2 promoter are used as a promoter to drive the expression of a gene specifically into endothelial cells, preferably said gene is a therapeutic gene, such as F...