ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,531, issued on Dec. 2, was assigned to UMC UTRECHT HOLDING B.V. (Utrecht, Netherlands).

"Methods for preparing nucleic acid molecules for sequencing" was invented by Wigard Pieter Kloosterman (Utrecht, Netherlands), Jeroen de Ridder (Utrecht, Netherlands) and Alessio Marcozzi (Utrecht, Netherlands).

According to the abstract* released by the U.S. Patent & Trademark Office: "Means and methods for preparing double stranded target DNA molecules for sequencing. In embodiments double stranded backbone DNA molecules comprising 5' and 3deg ends are provided that are: ligation compatible with 5' and 3' ends of the target DNA; form a first restriction enzyme recognition site when self-liga...