US Patent Issued to UCL Business on June 17 for "T cell which expresses a gamma-delta t cell receptor (TCR) and a chimeric antigen receptor (CAR)" (British Inventors)

ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,316, issued on June 17, was assigned to UCL Business Ltd (London).

"T cell which expresses a gamma-delta t cell receptor (TCR) and a chimeric antigen receptor (CAR)" was invented by John Anderson (London), Jonathan Fisher (London), Martin Pule (London) and Kenth Gustafsson (London).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a T cell which expresses a gamma-delta T cell receptor (TCR) and a chimeric antigen receptor (CAR), wherein the CAR comprises: an antigen binding domain; a transmembrane domain; and a co-stimulatory intracellular signalling domain; wherein the intracellular signalling domain provides a co-stimula...