ALEXANDRIA, Va., Jan. 29 -- United States Patent no. 12,209,262, issued on Jan. 28, was assigned to UCL Business LTD (London).
"Factor IX encoding nucleotides" was invented by Amit Nathwani (London) and Jenny Mcintosh (London).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to polynucleotides comprising a Factor IX nucleotide sequence, wherein the Factor IX nucleotide sequence comprises a coding sequence that encodes a Factor IX protein or fragment thereof and wherein a portion of the coding sequence is not wild type. The present invention further relates to viral particles comprising a recombinant genome comprising the polynucleotide of the invention, compositions comprising the ...