US Patent Issued to UCL BUSINESS, ST. JUDE CHILDREN'S RESEARCH HOSPITAL, THROMBOSIS RESEARCH INSTITUTE on March 25 for "Optimised coding sequence and promoter" (British, American Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,319, issued on March 25, was assigned to UCL BUSINESS LTD (London), ST. JUDE CHILDREN'S RESEARCH HOSPITAL (Memphis, Tenn.) and THROMBOSIS RESEARCH INSTITUTE (London).

"Optimised coding sequence and promoter" was invented by Amit Nathwani (London), Natalie Ward (London), Adrian Thrasher (London), Edward Tuddenham (London), John McVey (London), John Gray (Memphis, Tenn.) and Andrew Davidoff (Memphis, Tenn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "An optimized coding sequence of human blood clotting factor eight (VIII) and a promoter may be used in vectors, such as rAAV, for introduction of factor VIII, and/or other blood clotting factors and tr...