US Patent Issued to UCB BIOPHARMA on Nov. 18 for "Complexes between CD40 and compounds comprising benzimidazole moieties" (British Inventors)

ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,474,348, issued on Nov. 18, was assigned to UCB BIOPHARMA SRL (Brussels).

"Complexes between CD40 and compounds comprising benzimidazole moieties" was invented by James Philip O'Connell (Slough, Great Britain), John Robert Porter (Slough, Great Britain), Alastair Lawson (Slough, Great Britain), Boris Kroeplien (Slough, Great Britain), Stephen Edward Rapecki (Slough, Great Britain), Timothy John Norman (Slough, Great Britain) and Graham John Warrellow (Slough, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "It has been demonstrated that certain compounds bind to TNF and stabilise a conformation of trimeric TNF that binds to the TNF receptor....