US Patent Issued to UCB BIOPHARMA on June 10 for "Multi-domain proteins with increased native state colloidal stability" (British Inventors)

ALEXANDRIA, Va., June 18 -- United States Patent no. 12,327,614, issued on June 10, was assigned to UCB BIOPHARMA SRL (Brussels).

"Multi-domain proteins with increased native state colloidal stability" was invented by Ralph Adams (Slough, Great Britain), James Heads (Slough, Great Britain), Sebastian Kelm (Slough, Great Britain) and Alastair David Griffiths Lawson (Slough, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a method for generation of multi-domain proteins, more particular antibodies, with an improved native state colloidal stability. The present disclosure provides a method of producing an IgG1 or IgG4 antibody with an improved colloidal stability comp...