US Patent Issued to TYRIS THERAPEUTICS on Jan. 13 for "Process for the production of closed linear DNA" (Spanish Inventor)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,864, issued on Jan. 13, was assigned to TYRIS THERAPEUTICS S.L. (Moncada, Spain).

"Process for the production of closed linear DNA" was invented by Julen Oyarzabal Santamarina (Madrid).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a process for the production of a closed linear DNA comprising the steps of (a) providing a DNA template comprising a DNA sequence of interest; (b) amplifying DNA from the DNA template of step (a) wherein the amplification is primed with a primase/polymerase enzyme; (c) generating a closed linear DNA with the amplified DNA produced in step (b); and (d) purifying the closed linear DNA produced...