US Patent Issued to Turning Point Therapeutics on May 27 for "Chiral diaryl macrocycles and uses thereof" (New Jersey Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,310,968, issued on May 27, was assigned to Turning Point Therapeutics Inc. (Princeton, N.J.).

"Chiral diaryl macrocycles and uses thereof" was invented by Jingrong J. Cui (Princeton, N.J.), Yishan Li (Princeton, N.J.), Evan W. Rogers (Princeton, N.J.), Dayong Zhai (Princeton, N.J.), Wei Deng (Princeton, N.J.) and Zhongdong Huang (Princeton, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure relates to the use of certain diaryl macrocycle compounds, specifically (7S13R)-11-fluoro-7,13-di-methyl-6,7,13,14-tetrahydro-1,15-ethenopyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotridecin-4(5H)-one in the treatment of disease in mammals. This disclo...