US Patent Issued to Tufts Medical Center on May 27 for "Pyridopyrimidine compounds and methods of their use" (Massachusetts Inventor)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,346, issued on May 27, was assigned to Tufts Medical Center Inc. (Boston).

"Pyridopyrimidine compounds and methods of their use" was invented by Miaofen G. Hu (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are compounds of formula (I) or a pharmaceutically acceptable salt thereof, where X is O or S; R1 is hydrogen, an optionally substituted C1-6 alkyl, or an optionally substituted C3-8 cycloalkyl; each of R2, R3, and R4 is independently hydrogen, halo, or an optionally substituted C1-6 alkyl; R5 is a substituted C3 heteroaryl; and R6 is hydrogen or an optionally substituted C1-6 alkyl. Also disclosed are pharmaceutical compositions...