US Patent Issued to TSUBOTA LABORATORY on Nov. 25 for "Mouse myopia-induced model and endoplasmic reticulum stress suppressant for preventing and suppressing myopia" (Japanese Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,597, issued on Nov. 25, was assigned to TSUBOTA LABORATORY INC. (Tokyo).

"Mouse myopia-induced model and endoplasmic reticulum stress suppressant for preventing and suppressing myopia" was invented by Shinichi Ikeda (Tokyo), Xiaoyan Jiang (Tokyo), Kazuo Tsubota (Tokyo) and Toshihide Kurihara (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "A model that closely resembles human excessive myopia can be prepared by mounting a minus lens (2) and a protector (4) to a juvenile mouse, the minus lens having an angle and a width adjustable in response to growth of the mouse. Further, this model analysis shows that myopia induction causes endoplasmic reti...