ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,252, issued on Sept. 9, was assigned to Trustees of Tufts College (Medford, Mass.).
"Anti-PD-1 immunoglobulin polypeptides and uses thereof" was invented by Peter A. Bullock (Medford, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure relate to PD-1 binding proteins comprising immunoglobulin domains which bind specifically to PD-1 and comprise at least three or six specific complementarity determining regions (CDRs) and which comprise a specific feature in a variable domain framework region(s), e.g., heavy variable domain framework 1, heavy domain framework 4, and/or light chain variable domain framework 3 region(s). In ...